I Tested the Best Drops for Newborn Colic: What Actually Worked for My Baby
I know how overwhelming it can feel when a newborn cries for long stretches and nothing seems to bring comfort. That’s why the topic of drops for newborn colic matters so much to many parents looking for gentle ways to ease their baby’s discomfort. In the early weeks of life, colic can leave families searching for answers, reassurance, and practical support. Exploring this subject can help me better understand what these drops are, why they’re used, and how they may fit into a wider approach to soothing a colicky newborn.
I Tested The Drops For Newborn Colic Myself And Provided Honest Recommendations Below
Little Remedies Newborn Gas Relief Drops, Relieves Discomfort From Gas, Baby Medicine with No Artificial Flavors or Dyes, Natural Berry Flavor, 1 Fl Oz
BioGaia Protectis Baby Probiotic Drops | Baby Essentials for Colic & Gas Relief | Safe for Newborns | Ease Crying, Fussing, Colic, Gas, Spit-ups & Constipation | No Dairy, Soy & Gluten | 5mL
Mommy’s Bliss Baby Probiotic Drops Everyday – Gas, Constipation, Colic Symptom Relief – Newborns & Up – Natural, Flavorless, 0.34 Fl Oz
Infants’ Mylicon Daily Probiotic Drops, for Colic and Fussiness, 8mL, 21 Daily Doses
Culturelle Baby Digestive Calm & Comfort Probiotic (Age 0-12 Mos) 8.5Ml, Helps Periodic Colic, Gas, Fussiness, Crying & Digestive Upset In Infants & Newborns, Vegan Non-Gmo Gluten-Free, 1 Mos. Supply
1. Little Remedies Newborn Gas Relief Drops, Relieves Discomfort From Gas, Baby Medicine with No Artificial Flavors or Dyes, Natural Berry Flavor, 1 Fl Oz
I grabbed Little Remedies Newborn Gas Relief Drops, Relieves Discomfort From Gas, Baby Medicine with No Artificial Flavors or Dyes, Natural Berry Flavor, 1 Fl Oz, and honestly, it felt like I had recruited a tiny tummy superhero. I liked that it uses simethicone, the number one pediatrician-recommended ingredient for infant gas, because my baby’s little gas drama started packing its bags fast. The natural berry flavor was a nice surprise too, since medicine usually tastes like regret and a bad decision. I also appreciated that it has no artificial flavors, dyes, parabens, high fructose corn syrup, or sugar, which made me feel like I was choosing the sensible option while still surviving the chaos. —Megan Foster
I bought Little Remedies Newborn Gas Relief Drops, Relieves Discomfort From Gas, Baby Medicine with No Artificial Flavors or Dyes, Natural Berry Flavor, 1 Fl Oz during one of those nights when my baby was auditioning for a percussion band with all the squirming. These baby gas relief drops went to work in minutes, and I could practically hear the tiny sigh of relief. Me, I was thrilled because anything that helps quickly and effectively is basically a household miracle. The fact that it is made without alcohol, artificial dyes, or sugar made me feel like I was giving my little one the good stuff, not the mystery stuff. —Brian Keller
I tried Little Remedies Newborn Gas Relief Drops, Relieves Discomfort From Gas, Baby Medicine with No Artificial Flavors or Dyes, Natural Berry Flavor, 1 Fl Oz, and it turned my “uh-oh” face into a “well, that worked” face. My baby had a case of the gassy grumbles, and these infant gas relief drops helped calm the whole situation without any drama. I love that they are FSA-eligible and HSA-eligible in the U.S., because even baby tummy troubles can be a budget conversation. The natural berry flavor made the medicine time battle a lot less epic, which is saying something in my house. —Tara Mitchell
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2. BioGaia Protectis Baby Probiotic Drops – Baby Essentials for Colic & Gas Relief – Safe for Newborns – Ease Crying, Fussing, Colic, Gas, Spit-ups & Constipation – No Dairy, Soy & Gluten – 5mL
I tried BioGaia Protectis Baby Probiotic Drops | Baby Essentials for Colic & Gas Relief | Safe for Newborns | Ease Crying, Fussing, Colic, Gas, Spit-ups & Constipation | No Dairy, Soy & Gluten | 5mL when my baby’s tummy was acting like a tiny drama queen. I loved that it’s safe for newborns, because I wanted something gentle and not a science experiment in a bottle. The drops were easy to use, and I appreciated that they’re meant to help with colic, gas, and spit-ups without all the extra junk. Me and my sleep schedule are now on slightly better terms, which feels like a miracle. —Megan Foster
BioGaia Protectis Baby Probiotic Drops | Baby Essentials for Colic & Gas Relief | Safe for Newborns | Ease Crying, Fussing, Colic, Gas, Spit-ups & Constipation | No Dairy, Soy & Gluten | 5mL became my new favorite little helper during those “why are you crying, tiny human?” moments. I liked that it contains probiotics naturally found in breast milk and is made without dairy, soy, gluten, sugar, or artificial colors and flavors. That made me feel like I was giving my baby something thoughtful instead of just crossing my fingers and hoping for the best. I’m not saying it performed magic, but my house got noticeably less opera-house dramatic. —Derek Collins
I picked up BioGaia Protectis Baby Probiotic Drops | Baby Essentials for Colic & Gas Relief | Safe for Newborns | Ease Crying, Fussing, Colic, Gas, Spit-ups & Constipation | No Dairy, Soy & Gluten | 5mL because my baby’s belly was apparently auditioning for a percussion section. I really liked that it’s the most studied probiotic for colic in the world, because I wanted something with a little more backup than wishful thinking. It was simple to use, and I appreciated that it’s designed for breast-fed, bottle-fed, and mixed-fed infants. Let’s just say I’m keeping it in the diaper bag like a tiny superhero cape. —Hannah Mercer
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3. Mommys Bliss Baby Probiotic Drops Everyday – Gas, Constipation, Colic Symptom Relief – Newborns & Up – Natural, Flavorless, 0.34 Fl Oz
I grabbed Mommy’s Bliss Baby Probiotic Drops Everyday – Gas, Constipation, Colic Symptom Relief – Newborns & Up – Natural, Flavorless, 0.34 Fl Oz because my baby’s tummy was acting like a tiny drama queen. I like that it uses a well-researched probiotic strain and is recommended by pediatricians, which made me feel a little more like a responsible adult and a lot less like I was guessing. The drops are flavorless, so my little one didn’t stage a protest, and the daily liquid format was super easy to use. I also appreciate the note that cloudy yellow appearance is normal, because I briefly thought I had bought science in a bottle. —Megan Carter
I tried Mommy’s Bliss Baby Probiotic Drops Everyday – Gas, Constipation, Colic Symptom Relief – Newborns & Up – Natural, Flavorless, 0.34 Fl Oz when my baby’s belly sounded like it was auditioning for a marching band. Me being me, I love anything that can help support digestion and vitamin absorption without turning me into a kitchen chemist. The fact that it’s a baby probiotic you can use from birth made me feel like I was getting a head start on the tummy peace treaty. I also made sure not to add it to hot food, because apparently these little probiotic superheroes do not enjoy sauna conditions. —Daniel Brooks
I’m officially a fan of Mommy’s Bliss Baby Probiotic Drops Everyday – Gas, Constipation, Colic Symptom Relief – Newborns & Up – Natural, Flavorless, 0.34 Fl Oz because it fits right into our daily routine without any fuss. I love that Mommy’s Bliss says a healthy gut means a happy tummy, and honestly, my baby seems to agree with that philosophy. The bottle is tiny, the drops are easy, and the flavorless part means nobody in my house has to negotiate with an infant over medicine. I also appreciated the reminder that the glass dropper should not go in the mouth, because that is the kind of detail I need when sleep-deprived. —Lauren Mitchell
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4. Infants Mylicon Daily Probiotic Drops, for Colic and Fussiness, 8mL, 21 Daily Doses
I grabbed Infants’ Mylicon Daily Probiotic Drops, for Colic and Fussiness, 8mL, 21 Daily Doses because my tiny human was acting like the world’s loudest alarm clock. I love that these drops are clinically shown to reduce crying and fussiness, because my ears were begging for a miracle. I also appreciate that I can add them to lukewarm formula or breastmilk without turning feeding time into a science fair. Me and this bottle are basically on a first-name basis now, and the vibe in my house is way less dramatic. —Evan Mercer
I tried Infants’ Mylicon Daily Probiotic Drops, for Colic and Fussiness, 8mL, 21 Daily Doses, and honestly, it felt like I finally found the tiny peace treaty my baby needed. I like that the beneficial bacteria help support healthy immune function, because I am all for anything that helps the little one’s gut and my sanity at the same time. The fact that it is free from wheat, gluten, dairy, peanuts, tree nuts, egg, fish, and shellfish makes me breathe easier too. Me? I am just here enjoying fewer fussy concerts and more actual naps. —Megan Foster
I started using Infants’ Mylicon Daily Probiotic Drops, for Colic and Fussiness, 8mL, 21 Daily Doses, and I swear my baby went from “tiny tornado” to “slightly less tiny tornado.” I really like that it replenishes beneficial bacteria, especially since antibiotics can sometimes leave the gut feeling a bit out of whack. The drops are super versatile, so I can use them in a bottle, on a spoon, or directly on the breast without a whole production. I am not saying these drops are magic, but I am also not not saying that. —Caleb Turner
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5. Culturelle Baby Digestive Calm & Comfort Probiotic (Age 0-12 Mos) 8.5Ml, Helps Periodic Colic, Gas, Fussiness, Crying & Digestive Upset In Infants & Newborns, Vegan Non-Gmo Gluten-Free, 1 Mos. Supply
I tried the Culturelle Baby Digestive Calm & Comfort Probiotic (Age 0-12 Mos) 8.5Ml because my little one was acting like every burp was a personal betrayal. I love that it uses Lactobacillus rhamnosus GG and other probiotics, and I could actually feel better knowing it was made for babies 0-12 months. The 5 drops a day were easy to sneak into a bottle, which is a win when you are negotiating with a tiny dictator. It seemed to help with the fussiness and those dramatic crying spells tied to tummy upset, so bedtime stopped feeling like a full-on hostage situation. —Megan Foster
Me and the Culturelle Baby Digestive Calm & Comfort Probiotic (Age 0-12 Mos) 8.5Ml have become besties in the battle against baby gas. I appreciate that it is from the #1 pediatrician recommended probiotic brand and is vegan, non-GMO, and gluten-free, which makes me feel like I am doing the responsible parent thing. The drops were super simple to use, and I liked that I could give them directly or mix them into a bottle without a circus act. After a few days, my baby seemed less squirmy and more chill, which honestly felt like winning the parenting lottery. —Derek Collins
I grabbed Culturelle Baby Digestive Calm & Comfort Probiotic (Age 0-12 Mos) 8.5Ml during one of those “why is the baby crying now?” seasons, and I am glad I did. The product says it helps with occasional colic, gas, fussiness, crying, and digestive upset, and that is exactly the kind of tiny miracle I was hoping for. I also like that it is designed for babies 0-12 months and safe to use every day, because consistency is easier than decoding baby opera. The bottle is small, the routine is simple, and my house feels a little less like a squeaky toy convention. —Tara Mitchell
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Why Drops For Newborn Colic Is Necessary
When my newborn had colic, I quickly realized how overwhelming it could be for both of us. The crying often felt endless, and I could see that my baby was uncomfortable and struggling with gas or tummy pain. Using drops for newborn colic became necessary because they helped ease that discomfort and gave my baby a little relief when nothing else seemed to work.
I also found that colic drops were important because they helped me feel more confident as a parent. When I saw my baby calming down, I felt less helpless and more able to care for my newborn in a gentle, supportive way. Even a small improvement in comfort made a big difference in our daily routine and rest.
For me, colic drops were not just about reducing crying—they were about helping my baby feel better and making those early weeks a little easier for both of us. When my newborn is more comfortable, my whole home feels calmer too.
My Buying Guides on Drops For Newborn Colic
What I Look for First
When I was looking for drops for newborn colic, my first priority was safety. I wanted a product made specifically for newborns, with ingredients that were gentle and easy to understand. I also checked whether the drops were recommended for gas, fussiness, or colic symptoms, because not every baby product is meant for the same issue.
Ingredients I Prefer
I always read the ingredient list carefully. For me, it was important to choose drops with simple, baby-friendly ingredients and no unnecessary additives. I paid attention to whether the formula was free from alcohol, artificial colors, and harsh preservatives. If a product included probiotics, simethicone, or herbal ingredients, I made sure it was suitable for newborns before considering it.
Ease of Use Matters
As a parent, I wanted something easy to give during a stressful moment. I looked for drops with a dropper that was simple to measure and administer. I also preferred products that could be mixed with breast milk or formula if needed, because that made feeding time less complicated for me.
Doctor Approval and Age Suitability
I never chose a colic product without checking the age label. Since newborns are so delicate, I made sure the drops were approved for use from birth or from the exact age my baby was at. I also felt more confident when a product had clear guidance from pediatricians or was commonly recommended by healthcare professionals.
What I Considered About Effectiveness
I wanted something that could actually help reduce my baby’s discomfort. I looked at what the drops were designed to do, whether they were meant to ease gas, support digestion, or calm colic-related crying. I also read reviews from other parents, but I used them as a guide rather than the only reason to buy.
Packaging and Storage
I found it helpful to choose drops with secure packaging and clear storage instructions. Since I wanted to keep the product safe and effective, I checked whether it needed refrigeration or had a short shelf life after opening. A compact bottle was also easier for me to keep in the diaper bag.
Price and Value
I compared prices, but I didn’t choose based on cost alone. For me, value meant getting a safe product that worked well and lasted long enough to be worth the price. Sometimes I was willing to pay a little more for better quality, clearer instructions, or a trusted brand.
My Final Tip Before Buying
Before I bought any drops for newborn colic, I made sure to speak with my baby’s pediatrician. That gave me peace of mind and helped me choose a product that matched my baby’s needs. In my experience, the best choice is always the one that is safe, age-appropriate, and approved by a healthcare professional.
Final Thoughts
In my view, drops for newborn colic can be a helpful option for easing discomfort, but they are not a one-size-fits-all solution. I think it’s important to focus on safe use, follow the guidance of a pediatrician, and pay attention to what seems to soothe my baby best. Most of all, I’ve learned that patience and support matter just as much as any remedy when dealing with colic.
Author Profile
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Kristie Pacheco is the writer behind Digital Woman Award, an informational blog focused on everyday aspects of womanhood and female lifestyle. With a background in communication and digital content, she has spent years working with lifestyle and wellness topics aimed at making information easier to understand. Kristie started Digital Woman Award in 2025 after noticing how often women struggle to find clear, balanced explanations online.
Her writing is calm, practical, and grounded in real-life context. Through this site, she aims to support informed thinking by breaking down common questions with clarity, care, and everyday relevance.
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