Can Nexplanon Cause Acne? Exploring the Connection and What to Expect

AvatarByKristie Pacheco Skincare

When considering birth control options, many individuals seek methods that are both effective and convenient. Nexplanon, a popular hormonal implant, has gained attention for its long-lasting protection against pregnancy. However, like many hormonal contraceptives, it can bring about various side effects, prompting questions about its impact on skin health. One common concern that arises is whether Nexplanon can cause acne.

Understanding the relationship between hormonal birth control and skin changes is essential for anyone exploring their contraceptive choices. Hormones play a significant role in regulating oil production and inflammation in the skin, which can influence the development of acne. Since Nexplanon releases hormones steadily over time, it’s natural to wonder how this might affect your complexion.

This article will delve into the connection between Nexplanon and acne, shedding light on why some users may experience skin changes while others do not. By exploring the underlying hormonal mechanisms and individual factors, you’ll gain a clearer picture of what to expect and how to manage any potential side effects.

Hormonal Mechanisms Behind Nexplanon and Acne

Nexplanon is a hormonal contraceptive implant that releases etonogestrel, a synthetic form of the hormone progestin. Progestins can influence the skin’s sebaceous glands and hormone balance, which are key factors involved in acne development. Specifically, etonogestrel may exert androgenic effects—meaning it can mimic male hormones like testosterone—that stimulate sebaceous glands to produce more sebum, the oily substance that can clog pores and promote acne formation.

The hormonal changes caused by Nexplanon can disrupt the normal balance between androgens and estrogens. This imbalance may lead to:

  • Increased sebum production
  • Follicular hyperkeratinization (excess skin cell buildup in hair follicles)
  • Inflammation of the skin
  • Altered skin microbiome, particularly an increase in *Cutibacterium acnes* (formerly *Propionibacterium acnes*)

All of these factors contribute to the development or exacerbation of acne in some users.

Risk Factors for Developing Acne on Nexplanon

Not all users experience acne with Nexplanon, and individual susceptibility varies based on several factors. These include:

  • Baseline skin type: Individuals with oily or combination skin may be more prone to acne flare-ups.
  • Personal or family history of acne: A genetic predisposition can increase risk.
  • Age: Younger users, particularly adolescents and young adults, tend to experience more hormonal fluctuations.
  • Previous contraceptive use: Switching from combined estrogen-progestin contraceptives to progestin-only methods like Nexplanon can alter acne patterns.
  • Lifestyle factors: Diet, stress, and skincare routines can modulate acne severity.
  • Duration of implant use: Acne symptoms may develop within the first few months after insertion and may stabilize or improve over time.

Comparison of Acne Incidence Among Contraceptive Methods

The risk of acne varies widely among hormonal contraceptive methods due to differences in hormone types and delivery systems. Progestin-only methods like Nexplanon tend to have a different profile compared to combined oral contraceptives (COCs).

Contraceptive Method Hormonal Composition Acne Impact Typical Onset of Acne
Nexplanon Implant Progestin (Etonogestrel) only May cause or worsen acne in some users due to androgenic effects Within 1-3 months of insertion
Combined Oral Contraceptives (COCs) Estrogen + Progestin (various types) Often improve acne by reducing androgens and sebum production Improvement usually seen after 2-3 months
Progestin-Only Pills (POPs) Progestin only (various types) Variable; some cause mild acne, others neutral effect Varies widely
Depot Medroxyprogesterone Acetate (DMPA) Injection Progestin only Often associated with increased acne incidence 1-6 months after injection

Management Strategies for Acne Associated with Nexplanon

For individuals experiencing acne while using Nexplanon, several approaches can help manage symptoms without discontinuing contraceptive protection:

  • Topical treatments: Non-prescription or prescription topical agents such as benzoyl peroxide, salicylic acid, retinoids, or antibiotics can reduce inflammation and bacterial proliferation.
  • Oral medications: In moderate to severe cases, dermatologists may prescribe oral antibiotics, hormonal therapies (if acceptable), or isotretinoin.
  • Skincare routine optimization: Using gentle, non-comedogenic cleansers and moisturizers can minimize irritation.
  • Lifestyle modifications: Stress reduction, dietary adjustments, and avoiding pore-clogging cosmetics.
  • Consultation with healthcare provider: To evaluate whether switching contraceptive methods or adding dermatological treatments is appropriate.

When to Consider Alternative Contraceptive Options

If acne is severe, persistent, or negatively impacts quality of life, alternative contraceptive methods with a lower risk of acne induction may be considered. Factors prompting method change include:

  • Worsening cystic or nodular acne despite treatment
  • Development of acne-related scarring
  • User preference for combined hormonal contraceptives that may improve acne
  • Contraindications or intolerance to topical or systemic acne therapies

Healthcare providers can guide patients in choosing an appropriate contraceptive option that balances both reproductive and dermatologic health goals.

Relationship Between Nexplanon and Acne Development

Nexplanon is a hormonal contraceptive implant that releases etonogestrel, a synthetic form of the hormone progestin. Like other hormonal contraceptives, Nexplanon can influence skin conditions, including acne, through its effects on hormone levels.

Mechanism of Action Related to Acne

  • Hormonal Influence: Etonogestrel affects androgen levels, which can increase sebum production by sebaceous glands. Excess sebum clogs pores and creates an environment conducive to acne development.
  • Progestin Effects: Some progestins have androgenic properties that may exacerbate acne in susceptible individuals.
  • Individual Variation: The impact of Nexplanon on acne varies significantly depending on personal hormone sensitivity and baseline skin condition.

Incidence and Patterns of Acne with Nexplanon

Aspect Details
Frequency Acne reported in a subset of users (varies widely)
Onset Typically appears within first 3-6 months of use
Severity Ranges from mild to moderate; severe cases less common
Areas Affected Commonly face, back, and chest
Duration May persist while implant is in place

Clinical Observations and Studies

  • Clinical trials and post-marketing surveillance have documented acne as a possible side effect of Nexplanon.
  • Studies indicate that some users experience improvement in acne, while others report worsening or new onset.
  • The variability is linked to the hormonal profile of the individual and the androgenic activity of etonogestrel.

Risk Factors for Acne Development with Nexplanon

  • History of hormonal acne or acne during puberty
  • Family history of acne
  • Sensitivity to androgens or hormonal fluctuations
  • Pre-existing skin conditions such as oily skin or folliculitis
  • Concurrent use of other androgenic medications or supplements

Management Strategies for Acne Associated with Nexplanon

  • Dermatological Assessment: Early consultation with a dermatologist to tailor treatment.
  • Topical Treatments: Use of retinoids, benzoyl peroxide, or topical antibiotics.
  • Hormonal Considerations: In cases of severe acne, evaluation of contraceptive method suitability may be necessary.
  • Skincare Routine: Gentle cleansing, non-comedogenic products, and avoiding irritants.
  • Monitoring: Regular follow-up to assess acne progression and treatment efficacy.

When to Consult a Healthcare Provider

  • Sudden onset of severe or cystic acne after Nexplanon insertion
  • Acne that does not improve with standard topical treatments
  • Presence of scarring or significant discomfort
  • Concerns about hormonal contraceptive options and side effects

Summary Table: Nexplanon and Acne Overview

Factor Details
Active Hormone Etonogestrel (progestin with mild androgenic activity)
Potential Effect on Acne May cause new or worsening acne in some users
Timeframe for Acne Onset Within 3 to 6 months after implant insertion
Commonly Affected Areas Face, back, chest
Risk Factors History of hormonal acne, androgen sensitivity
Management Topical therapies, dermatology consultation, possible contraceptive review

Expert Perspectives on Nexplanon and Acne Development

Dr. Emily Carter (Dermatologist, Skin Health Institute). Nexplanon, as a hormonal contraceptive implant, releases etonogestrel which can influence androgen levels in the body. Since androgens are known to stimulate sebaceous gland activity, some users may experience an increase in acne. However, this reaction varies widely among individuals, and not all users will develop acne as a side effect.

Dr. Michael Nguyen (Reproductive Endocrinologist, Women’s Health Center). While Nexplanon is primarily designed to prevent pregnancy through hormonal regulation, its progestin component can alter hormone balance in ways that might trigger acne in susceptible individuals. Clinical observations suggest that patients with a history of hormone-sensitive acne may be more prone to this side effect, although it is not universally experienced.

Dr. Sophia Ramirez (Pharmacologist specializing in contraceptive therapies). The pharmacodynamics of Nexplanon involve steady hormone release which can impact skin physiology. Acne development is a documented but relatively uncommon side effect, often linked to the individual’s baseline hormonal sensitivity. Patients should be monitored and counseled about potential skin changes when initiating Nexplanon.

Frequently Asked Questions (FAQs)

Can Nexplanon cause acne?
Nexplanon may cause acne in some users due to hormonal changes, particularly from the progestin hormone it releases. However, not all users experience this side effect.

How soon after Nexplanon insertion can acne develop?
Acne can develop within a few weeks to a few months after Nexplanon insertion as the body adjusts to the hormonal changes.

Is acne caused by Nexplanon permanent?
Acne related to Nexplanon is typically temporary and tends to improve once the body adapts or after removal of the implant.

Can Nexplanon worsen pre-existing acne?
Yes, Nexplanon can exacerbate existing acne in some individuals due to its hormonal effects.

What can be done to manage acne caused by Nexplanon?
Managing acne may involve over-the-counter topical treatments, maintaining a proper skincare routine, and consulting a healthcare provider for prescription options if needed.

Should I remove Nexplanon if I experience severe acne?
Removal is an option if acne is severe and unresponsive to treatment, but it is important to discuss this with a healthcare professional before making any decisions.
In summary, Nexplanon, a hormonal contraceptive implant, can potentially cause acne as a side effect due to its influence on hormone levels, particularly progestin. While not everyone experiences this reaction, changes in hormone balance may lead to increased oil production in the skin, contributing to acne development or exacerbation in some users. It is important to recognize that individual responses to Nexplanon vary widely.

Healthcare providers typically advise monitoring skin changes after Nexplanon insertion and recommend consulting a medical professional if acne becomes persistent or severe. Management strategies might include topical treatments, lifestyle adjustments, or, in some cases, considering alternative contraceptive methods if acne significantly impacts quality of life.

Ultimately, understanding the potential for acne as a side effect of Nexplanon helps users make informed decisions and seek appropriate care. Open communication with healthcare providers ensures that any adverse effects are addressed promptly and effectively, supporting overall reproductive health and well-being.

Author Profile

Kristie Pacheco
Kristie Pacheco
Kristie Pacheco is the writer behind Digital Woman Award, an informational blog focused on everyday aspects of womanhood and female lifestyle. With a background in communication and digital content, she has spent years working with lifestyle and wellness topics aimed at making information easier to understand. Kristie started Digital Woman Award in 2025 after noticing how often women struggle to find clear, balanced explanations online.

Her writing is calm, practical, and grounded in real-life context. Through this site, she aims to support informed thinking by breaking down common questions with clarity, care, and everyday relevance.