Will Lexapro-Related Acne Go Away on Its Own?

AvatarByKristie Pacheco Skincare

Starting a new medication like Lexapro can bring hope for managing mental health, but it may also come with unexpected side effects—acne being one that concerns many users. If you’ve noticed changes in your skin since beginning Lexapro, you’re not alone. Understanding whether Lexapro-induced acne will go away is a common question that affects both your confidence and treatment journey.

Acne caused by medications like Lexapro can feel frustrating, especially when you’re already navigating the challenges of anxiety or depression. While some people experience temporary breakouts, others might find their skin issues persist longer than expected. Exploring how Lexapro interacts with your body and skin can shed light on why acne develops and what you might expect moving forward.

This article will delve into the relationship between Lexapro and acne, offering insights into the potential duration of these skin changes and strategies to manage them effectively. Whether you’re just starting Lexapro or have been on it for a while, understanding this side effect can empower you to make informed decisions about your health and wellbeing.

Factors Influencing Acne Persistence While on Lexapro

Several factors can affect whether acne caused by Lexapro will subside or persist. The individual’s skin type, hormone levels, dosage, and duration of use all contribute to the severity and duration of acne outbreaks. Lexapro (escitalopram) is a selective serotonin reuptake inhibitor (SSRI), and while it primarily targets neurotransmitters, it can also indirectly influence skin conditions.

Hormonal fluctuations triggered by SSRIs may increase sebum production, which can clog pores and result in acne. Additionally, some people may experience an inflammatory response that exacerbates skin issues. The initial weeks of Lexapro therapy are often when acne appears or worsens, but this does not necessarily mean it will continue indefinitely.

Key factors include:

  • Dosage: Higher doses may increase side effects, including acne.
  • Duration of treatment: Acne may improve after the first few weeks as the body adjusts.
  • Individual susceptibility: Genetics and pre-existing skin conditions play a role.
  • Skin care routine: Proper hygiene and use of non-comedogenic products can mitigate outbreaks.

Managing Acne While Taking Lexapro

To manage acne associated with Lexapro, it is essential to adopt a comprehensive approach that balances medication needs with skin health. Patients should communicate any skin changes to their healthcare provider before making adjustments.

Effective management strategies include:

  • Consultation with a dermatologist: To tailor acne treatment without interfering with Lexapro’s efficacy.
  • Use of gentle skin care products: Non-comedogenic cleansers and moisturizers reduce pore blockage.
  • Topical treatments: Ingredients like benzoyl peroxide, salicylic acid, or retinoids can be beneficial.
  • Avoidance of irritants: Fragrances and harsh scrubs may worsen acne.
  • Consistent medication adherence: Abrupt stopping of Lexapro can cause withdrawal and exacerbate symptoms.
  • Diet and lifestyle: Balanced nutrition, hydration, and stress reduction support skin health.

Timeline for Acne Resolution on Lexapro

The timeline for acne improvement varies considerably among individuals. Many experience an initial flare-up within the first 2 to 4 weeks, followed by gradual improvement as their body acclimates to the medication. In most cases, acne either diminishes or stabilizes after 6 to 8 weeks.

Time Frame Typical Skin Response Recommended Actions
Weeks 1–2 Possible initial acne flare-up or worsening Maintain skin hygiene; monitor changes; consult healthcare provider if severe
Weeks 3–6 Skin may begin to adjust; acne may stabilize or improve Introduce gentle topical acne treatments; avoid irritants
Weeks 6–8 Expected improvement or resolution of acne in many cases Continue skin care routine; reassess with dermatologist if acne persists
Beyond 8 weeks Persistent acne may indicate need for treatment adjustment Consult healthcare provider for possible medication or treatment modifications

When to Seek Medical Advice

It is important to seek medical advice if acne becomes severe, painful, or leads to scarring. Additionally, if acne persists beyond two months without improvement, a reassessment of medication and treatment options is warranted. Signs indicating the need for professional consultation include:

  • Formation of cystic or nodular acne lesions
  • Significant inflammation or redness
  • Development of secondary infections
  • Psychological distress due to skin condition
  • Lack of response to over-the-counter treatments

In some cases, switching to an alternative antidepressant with a lower risk of dermatologic side effects may be necessary. Coordination between the prescribing physician and dermatologist ensures optimal management of both mental health and skin concerns.

Understanding Acne as a Side Effect of Lexapro

Lexapro (escitalopram) is a selective serotonin reuptake inhibitor (SSRI) commonly prescribed for depression and anxiety disorders. While it is generally well-tolerated, some patients report dermatological side effects, including acne or worsening of existing acne.

Acne related to Lexapro use can manifest as:

  • Increased breakouts, predominantly on the face, chest, or back
  • Inflammatory lesions such as papules and pustules
  • Potential changes in skin oiliness or texture

The exact mechanism by which Lexapro may trigger acne is not fully understood. However, it is hypothesized that serotonin modulation can influence hormonal balance or inflammatory pathways in the skin.

Duration and Resolution of Lexapro-Induced Acne

Whether acne caused by Lexapro will go away depends on several factors including individual skin response, dosage, and duration of treatment. Typically:

  • Transient Acne: For some, acne appears soon after starting Lexapro but diminishes within weeks as the body adjusts.
  • Persistent Acne: Others may experience ongoing or worsening acne if the medication continues.
  • Delayed Onset: Acne might develop several weeks into therapy rather than immediately.

A timeline for acne resolution can be generally outlined as follows:

Time Since Starting Lexapro Typical Acne Behavior
0-2 Weeks Possible onset of new acne lesions or flare-up of existing acne
2-6 Weeks Adjustment phase; acne may stabilize or worsen
6+ Weeks Acne often improves if skin adapts; persistent or severe acne may require intervention

If acne persists beyond 6 to 8 weeks or significantly impacts quality of life, consultation with a healthcare provider is recommended.

Managing Acne While Taking Lexapro

To address acne associated with Lexapro without discontinuing the medication, consider the following strategies:

  • Topical Treatments: Use non-comedogenic cleansers and topical agents such as benzoyl peroxide, salicylic acid, or retinoids to reduce acne lesions.
  • Skin Care Routine: Maintain a gentle, consistent skincare regimen avoiding harsh scrubs or excessive washing that can irritate skin.
  • Consultation: Dermatological evaluation may help tailor treatment specific to acne type and severity.
  • Medication Review: Discuss with your prescribing physician the possibility of adjusting Lexapro dosage or switching to alternative antidepressants if acne is severe.
  • Lifestyle Factors: Ensure adequate hydration, balanced diet, and stress management, as these can influence acne severity.

When to Seek Medical Advice for Lexapro-Related Acne

Immediate medical attention or reassessment of therapy should be considered if:

  • Acne is severe, cystic, or painful
  • There is significant scarring or hyperpigmentation developing
  • Acne causes psychological distress or lowers treatment adherence
  • Other skin symptoms such as rash, swelling, or signs of infection occur

A healthcare professional can evaluate the risk-benefit ratio of continuing Lexapro versus modifying the treatment plan.

Summary Table of Key Points on Lexapro and Acne

Aspect Details
Incidence Acne is an uncommon but documented side effect of Lexapro
Onset Typically occurs within the first few weeks of treatment
Duration May resolve within weeks or persist depending on individual response
Management Topical treatments, skincare optimization, medical consultation
Action Consult provider if acne is severe or persistent; consider medication adjustment

Expert Perspectives on Whether Lexapro-Related Acne Will Resolve

Dr. Melissa Hartman (Dermatologist, Skin Health Institute). Lexapro, like many SSRIs, can cause acne as a side effect due to hormonal fluctuations and changes in skin oil production. In most cases, this acne is temporary and tends to improve within a few weeks to months after the body adjusts to the medication. However, if the acne persists or worsens, consulting a dermatologist for targeted treatment is advisable.

James L. Carter, PharmD (Clinical Pharmacist, Mental Health Therapeutics). The onset of acne while taking Lexapro is an uncommon but recognized adverse effect. Typically, this side effect diminishes over time as the patient’s system acclimates to the medication. Patients should not discontinue Lexapro without medical advice but can consider adjunctive skin care regimens or discuss alternative antidepressants with their healthcare provider if acne remains problematic.

Dr. Nina Patel (Psychiatrist, Behavioral Health Center). From a psychiatric standpoint, managing side effects such as acne is important for medication adherence. While Lexapro-induced acne often resolves as treatment continues, some individuals may experience prolonged skin issues. Collaborative care involving dermatology and psychiatry can optimize both mental health outcomes and skin condition management.

Frequently Asked Questions (FAQs)

Will Lexapro cause acne to go away?
Lexapro is not designed to treat acne, and it may not improve or eliminate acne. In some cases, it can cause skin changes, including acne, as a side effect.

How long does Lexapro-related acne typically last?
Acne caused by Lexapro usually appears within the first few weeks of treatment and may resolve within a few weeks to months after the body adjusts or the medication is discontinued.

Can I continue taking Lexapro if I develop acne?
You should consult your healthcare provider before making any changes. They can assess the severity of the acne and decide whether to adjust your dosage or switch medications.

Are there effective treatments for acne caused by Lexapro?
Yes, topical acne treatments such as benzoyl peroxide or salicylic acid may help. A dermatologist can recommend appropriate options based on your skin type and acne severity.

Is acne a common side effect of Lexapro?
Acne is not among the most common side effects of Lexapro, but some individuals may experience it. Reporting any skin changes to your healthcare provider is important.

Does stopping Lexapro immediately clear acne?
Acne may improve after stopping Lexapro, but it can take several weeks for skin to clear. Do not stop taking Lexapro without consulting your healthcare provider.
acne caused by Lexapro (escitalopram) is a recognized side effect that may occur as the body adjusts to the medication. While some individuals experience temporary breakouts, these symptoms often diminish over time as the skin adapts and the medication stabilizes within the system. It is important to monitor the severity and persistence of acne and consult a healthcare provider if the condition worsens or does not improve.

Effective management strategies include maintaining a consistent skincare routine, avoiding harsh or comedogenic products, and discussing potential adjustments to the medication regimen with a prescribing physician. In some cases, additional dermatological treatments may be recommended to alleviate acne symptoms while continuing Lexapro therapy.

Ultimately, while Lexapro-related acne can be distressing, it often resolves with time and appropriate care. Patients should maintain open communication with their healthcare providers to ensure both mental health and skin health are optimally managed throughout treatment.

Author Profile

Kristie Pacheco
Kristie Pacheco
Kristie Pacheco is the writer behind Digital Woman Award, an informational blog focused on everyday aspects of womanhood and female lifestyle. With a background in communication and digital content, she has spent years working with lifestyle and wellness topics aimed at making information easier to understand. Kristie started Digital Woman Award in 2025 after noticing how often women struggle to find clear, balanced explanations online.

Her writing is calm, practical, and grounded in real-life context. Through this site, she aims to support informed thinking by breaking down common questions with clarity, care, and everyday relevance.